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David Baker (U. Washington / HHMI) Part 1: Introduction to Protein Design
Current Trends in Protein Engineering: Updates and Progress.
Proteins are one of the most important and resourceful biomolecules that find applications in health, industry, medicine, research, and biotechnology. Given its tremendous relevance, protein engineering has emerged as significant biotechnological intervention in this area. Strategic utilization of protein engineering methods and approaches has enabled better enzymatic properties, better stability, increased catalytic activity and most importantly, interesting and wide range applicability of proteins. In fact, the commercialization of engineered proteins have manifested in economically beneficial and viable solutions for industry and healthcare sector. Protein engineering has also evolved to become a powerful tool contributing significantly to the developments in both synthetic biology and metabolic engineering. The present review revisits the current trends in protein engineering approaches such as rational design, directed evolution, de novo design, computational approaches etc. The review also throws light on advanced or futuristic protein engineering aspects, which are being explored for design and development of novel proteins with improved properties or advanced applications.
Skip to search form Skip to main content. It is based on the use of recombinant DNA technology to change amino acid sequences. View PDF. Save to Library. Create Alert.
It publishes research and reviews relevant to the engineering, design and selection of proteins. The community board offers expert and high-quality peer review with fast turnaround times. PEDS are currently inviting submissions for a special issue on computational protein design. Submissions are welcomed on all relevant subjects. PEDS are currently inviting submissions for a special issue on amyloids.